Had tried many treatment options with no success including levetiracetam, xcarbazepine, topiramate, zonisamide, valproate, clobazam, clonazepam, valium and the ketogenic diet By the time Charlotte was 5 years old:ĭiagnosed with Dravet Syndrome with a SCN1A gene mutation Įxperienced up to 50 generalized tonic-clonic seizures per day The following clinical research is representative of what currently exists regarding cannabinoids and epilepsy.Ĭharlotte Figi is a well-known case study in cannabinoids and epilepsy. Case studies like Charlotte Figi’s (‘Charlotte’s Web’) are useful in that they may open patients’ and doctors’ minds to an alternative treatment that is worth trying in certain cases based on risk, possibility, and the seriousness of a patient’s condition. It is important to remember, however, that statistics and case studies do not guarantee success with cannabinoid therapy for any particular patient, and it is best to keep expectations tempered as we still do not fully understand the mechanisms of cannabinoid anti-seizure activity. Įxamining case study and survey data may be helpful for patients and doctors to get an overview of probability of success and what may be possible. Up to 20% of epilepsy patients in the United States today use cannabis, many moving their families to states with medical cannabis laws specifically to pursue this therapy. Many patients have been willing to experiment with CBD. Nevertheless, the majority of information we have is positive, pointing to cannabinoids, particularly CBD, being an effective anti-seizure treatment. While much of this information is interesting, promising, and serves as proof that further research is warranted, both methods of data collection have drawbacks including reliability and applicability of the information to other patients. Most of the information we have regarding cannabinoids and epilepsy comes from case studies and surveys.
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